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For Patients

Hoag is committed to leading the way in state-of-the-art technologies and advanced treatment options. Part of this commitment involves conducting groundbreaking clinical research with the goal of helping patients live longer, healthier lives.

Through carefully planned clinical trials, researchers evaluate the safety and effectiveness of new ways to diagnose, treat and prevent diseases or conditions. Treatments studied in clinical trials might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments.

Possible Benefits of Clinical Trials

There are many potential benefits for clinical trial participants. Patients with existing diseases or conditions are able to take a more active role in their own health care, gain access to newly researched treatments before they are widely available, and help others by contributing to medical research.

Possible Drawbacks of Clinical Trials

New treatments being studied are not always better than, or even as good as, standard care. They may have side effects that are unexpected, or that are worse than those of standard care. As with standard treatments, the new treatment may not work for you even if it works for other patients.

In addition, insurance companies do not always cover all patient care costs in a study. What is covered varies by plan and by study.

If you decide to participate in a research study, you will be given contact information in case of severe side effects or an emergency. If the treatment you receive in the study turns out to be harmful, the study will be stopped.

Making an Informed Decision

  • Informed consent: Before deciding to participate in a study, you will receive an informational document called an Informed Consent Form. This form provides important facts about the study to help you decide if participating is right for you. Our research team will review this form with you and answer your questions. Although you must sign the informed consent form in order to participate in the study, it is not a contract. You may leave the study at any time for any reason. Your study records are private and confidential. Only the research team and your physician or nurse will have access to your records.
  • Risks and benefits: Every study is monitored to make sure it is as safe as possible. However, all medical research involves some level of risk. The risks and benefits vary depending on the particular study. To help you make an informed decision, the research team is required to inform you of all known risks, benefits and available alternative healthcare options.
  • Ask questions: Whether or not to take part in a clinical trial is your decision. So it’s important to take the time to fully understand the risks and benefits of the study by asking questions. You may wish to bring a family member or friend to help you ask questions and write down answers. For more information, download the FDA’s brochure.

Ensuring Clinical Trial Safety

Every clinical trial in the United States must be approved and monitored by an Institutional Review Board (IRB). An IRB is an independent committee of physicians, statisticians, community advocates and others whose objective is to ensure that a clinical trial is ethical and the rights of study participants are protected. The U.S. Food and Drug Administration (FDA) audits the IRB files, and may visit research providers at any time and review anything they choose related to clinical trials.

At Hoag, our clinical research team is committed to policies and practices for ethical conduct of human research. Hoag has a tradition of excellence in research and a continuing commitment to protect the interests and well being of patients. As such, Hoag strives to:

  • Protect the interest and well being of patients participating in clinical research at Hoag Hospital
  • Uphold regulations as set forth by the Federal Government concerning research on human subjects
  • Uphold the regulations set forth in the Nuremburg Code, International Conference on Harmonisation (ICH) and the Belmont Report
  • Uphold policies as set forth by Hoag Hospital

Review the available clinical trials at Hoag now. For more information about available clinical trials nationwide, visit or