Melanoma & Skin Cancer
16105 Sand Canyon Ave., Ste. 220, Irvine CA 92618
(949) 557-0275
- About
- Diagnosis & Treatment
- Mohs Surgery
- Vectra Total Body Photographic Imaging
- Meet the Team
- FAQ
Hoag’s multidisciplinary team delivers precise diagnosis and treatment for all skin cancers. Using Mohs surgery, Vectra WB360 3D imaging and innovative therapies, our specialists ensure early detection, effective care and the best possible outcomes.
Personalized Cancer Care
Hoag’s multidisciplinary team provides expert evaluation, staging, and highly personalized treatment planning, delivering outcomes that rank among the nation’s best.
Clinical Trials & Research
Through innovative clinical research, Hoag physicians explore the efficacy of new drugs, therapies, medical devices and clinical and surgical methods – ensuring you have access to the most advanced treatments available.
Supportive Resources
Hoag is the top choice for cancer care in Orange County, with cancer survival rates that continually exceed national averages. Our dedicated, world-class teams are wholly focused on helping you survive cancer, heal and move forward with your life.

Expert Skin Cancer Care at Hoag

Vectra WB360 3D Total Body Photographic Imaging

Dedicated Mohs Surgeon

All-Inclusive Care in One Location

Leader in Skin Cancer Research & Clinical Trials

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Contact usMelanoma & Skin Cancer Treatments
Mohs Surgery
Mohs surgery at Hoag offers you an exceptional cure rate with less scarring than traditional skin cancer surgery. Performed by our dedicated dermatologic oncologist, Mohs surgery removes all skin cancer, sparing healthy surrounding tissue.
Chemotherapy/Systemic Therapy
Chemotherapy uses powerful drugs or chemicals to directly attack cancerous cells. Systemic Therapy is a non-surgical treatment option for cancer patients. Systemic therapy is when drugs are administered into a patient’s blood stream to stop or slow the growth of cancerous cells. Biological therapy, also referred to as “Immunotherapy” utilizes the body immune system to fight cancer cells.
Radiation Oncology
Hoag’s Radiation Oncology Program offers the widest range of radiation therapy options available, ensuring every treatment plan is precisely tailored to each patient.
Stereotactic Body Radiation Therapy (SBRT)
Stereotactic Radiation Therapy (SRT) is an intermediate technique, with many of the characteristics of both Stereotactic Radiosurgery (SRS) and Image-Guided Intensity-Modulated Radiation Therapy (IG-IMRT). When applied outside of the brain, this technique is often called Stereotactic Body Radiation Therapy (SBRT).
Vectra WB360 3D Total Body Photographic Imaging
Hoag is the first and only hospital on the west coast to offer high-risk skin cancer patients access to the Vectra 360.
Precision Medicine Program
Hoag’s Precision Medicine Program combines genomics and genetics to diagnose, treat, and prevent diseases. Using the latest advances in genomic technologies, targeted therapies and research, our precision medicine program brings together a multidisciplinary team, including a robust genetic counseling group of experts, to provide patients with the latest in innovation and technology.
Tumor Boards
Tumor boards* are a meeting of Hoag’s top experts in their respective subspecialties to determine the best approach for a patient’s individual cancer case.
Palliative Care
Palliative care is a specialty that focuses on improving the quality of life of individuals facing serious illness through medical management and emotional support.
Cancer Clinical Trials
Early development clinical trials (phase I and II) are novel drug therapies that examine new treatments that provide options beyond standard of care. During these trials, researchers are carefully examining the best way to administer the treatment, determine how much can be safely given, identify important potential side effects, as well as assess cancer response.
Diagnosing & Treating Skin Cancers
Hoag is here for you. The Hoag Melanoma & Skin Cancer Program is a comprehensive path in Orange County for those seeking diagnosis and treatment for melanoma and non-melanoma cancers, such as basal cell, squamous cell and merkel cell cancers. Featuring a world-class roster of specialists in dermatologic oncology, surgical oncology, radiation oncology, hereditary cancer and skin cancer research, Hoag offers the experience and advanced technology you can rely on for high-risk monitoring, diagnosing and treatment of skin cancer.

Monitoring for Skin Cancer
Vectra WB360 Total Body Photography is available at Hoag – Hoag is the first hospital on the West Coast to offer high-risk skin cancer patients access to the Vectra WB360 as part of its comprehensive Melanoma & Skin Cancer Program. This breakthrough technology allows for whole-body monitoring of suspicious lesions and tracking changes over time.
Hereditary Skin Cancer – For more than a decade, Hoag has been Southern California’s leader in advanced genetic profiling to detect the presence or potential risk of developing certain cancers. Skin cancers that may be hereditary include:
Melanoma
Basal cell carcinoma
Squamous cell carcinoma
If you are concerned about an elevated risk due to a family history of skin cancer, learn more about Hoag’s Hereditary Cancer Program.
Diagnosing Skin Cancer
Early detection of skin cancer is key to improved outcomes and keeping the cancer from spreading. At Hoag, our skin cancer detection and dermatologic oncology program is second to none when it comes to the accurate, early diagnosis that saves lives. The type of skin cancer is usually determined by where the cancer begins, or which cells are cancerous. Some of these cell types include:
Squamous – found in the upper (outer) part of the epidermis. Squamous cell carcinoma starts in these cells.
Basal – found in the lower part of the epidermis. Basal cell carcinoma starts in these cells.
Melanocytes – these cells make the brown pigment called melanin which gives your skin its tan or brown color. Melanoma skin cancer starts in these cells.
Merkel – found in the top layer of the skin, very close to the nerve endings that receive the sensation of touch. Merkel cell carcinoma usually appears as a single painless lump on areas of the skin exposed to ultraviolet rays and is very rare.
If you visit a physician for a spot, mole, blemish or lump that gives you concern, the doctor will likely examine the spot and the rest of your skin, along with asking you questions about your symptoms and family history. If something concerning is found, a sample from the spot is removed and sent for testing. This is a painless procedure and will likely be done by either:
Punch biopsy
Excision
Our specialized team at Hoag includes a dedicated dermatologist whose only focus is the diagnosis of melanoma and other skin cancers. The benefits of coming to Hoag include:
Shorter waits for exams
In-depth knowledge and expertise
A chance to avoid the “biopsy first” approach
Fewer disfiguring scars and clearer, healthier skin
Access to high-risk management, biopsy, Mohs surgery, other surgical approaches and subspecialty medical oncologists.

Staging
If testing shows evidence of melanoma or a non-melanoma skin cancer, it is important to determine whether the cancer has spread, or metastasized, and how extensive it is. This is called staging and may be determined by:
Measuring the thickness of the skin cancer, a thicker melanoma means the disease has penetrated further into the skin and is a more serious case.
If needed, our surgical oncologist can perform a Sentinel Node Biopsy to see if there’s evidence the cancer has spread to nearby lymph nodes.
At Hoag, our expert pathologists specialize in skin cancer & melanoma diagnoses ensuring an accurate skin cancer diagnosis. Precision medicine may also be used to ensure a molecular-based diagnosis. Learn about Hoag’s Precision Medicine Program.

Second Opinion Consultations
Melanoma and other skin cancers should be handled by experienced, subspecialists who understand the complexity of the cancer and how to best treat it. For patients unsure about their current treatment pathway, Hoag’s Melanoma & Skin Cancer Program offers second opinion consultations. Contact us today for assistance with a second opinion.
Treatment Options for Skin Cancer
Hoag’s Melanoma & Skin Cancer Program has the most complete and comprehensive skin cancer program in Orange County. Our multidisciplinary team has special expertise in providing the most accurate diagnosis and effective treatment plans across all skin cancer types, including performing Mohs surgery. To help patients and their families through diagnosis and treatment to survivorship, our dedicated melanoma and skin cancer clinical nurse navigator acts as facilitator and guide. Treatment options for skin cancer depend on many factors, such as:
How advanced the cancer is when detected
Your age and any other health issues you may have
Rest assured, Hoag will provide you with world-class expertise and a personalized treatment plan specific to your needs.

Advanced Surgical Treatment at Hoag
The most common treatment for melanoma and non-melanoma skin cancers is surgical removal of that piece of tissue, which usually cures most early-stage lesions. When detected early, Hoag is a leader in performing Mohs Surgery, today’s least invasive surgical option for a full recovery from Melanoma and other skin cancers resulting in better outcomes and less scarring. If you are not a candidate for Mohs surgery, our surgical oncologist offers expertise in non-Mohs surgical interventions, including:
Surgical excision
Sentinel node biopsy
Lymph node dissection
Wide local excision
Through collaboration with Hoag plastic surgeons, patients are able to optimize their appearance and reduce the visibility of scars when needed.
If Skin Cancer Has Metastasized
At Hoag, treatment plans for metastasized skin cancers are personalized to meet the needs of each patient. Our treatment options offer the most recent advancements in techniques and technology, including:
Research & Clinical Trials for Skin Cancer
Hoag is committed to leading the way in state-of-the-art technologies and advanced treatment options. Part of this commitment includes clinical research with the goal of helping patients live longer, healthier lives. Through carefully planned clinical trials, researchers evaluate the safety and effectiveness of new ways to diagnose, treat and prevent diseases or conditions. Treatments studied in clinical trials might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments.
View clinical trials for melanoma and other skin cancers here.
Mohs Surgery
Mohs surgery at Hoag offers you an exceptional cure rate with less scarring than traditional skin cancer surgery. Performed by our dedicated dermatologic oncologist, Mohs surgery removes all skin cancer, sparing healthy surrounding tissue. Mohs surgery at Hoag provides:
An experienced team, dedicated solely to skin cancer
A Mohs surgeon with 20+ years of experience
A comfortable, spacious & caring environment
Treatments that are performed on an outpatient basis with local anesthesia.
Call for an appointment.
"Mohs surgery provides the highest cure rate and spares the maximal amount of normal surrounding skin."

Overview of Mohs Surgery
Mohs surgery is a type of surgery to treat skin cancer. It uses a special technique to remove ALL of the skin cancer but saves healthy tissue in order to limit scarring. Mohs surgery is the most effective treatment for skin cancer. It is often used to treat skin cancer that:
May be on areas of the body where keeping appearance and function are important
Has come back after being removed
Has aggressive behaviors
Covers a large area
Grows quickly
During your surgery, a layer of tissue will be removed from your skin and checked for cancer cells using a microscope. If there are cancer cells, more layers will be removed and checked for cancer cells. This will continue until all the skin cancer has been removed and the margins are clear.
You will not get general anesthesia (medication to make you sleep) during your surgery. You will receive a local anesthetic (medication to make an area of your body numb).
Talk with your health care provider about risks associated with Mohs surgery. Possible risks may include:
Pain or tenderness at the surgery site
Infection
Bleeding from the surgery site
Scarring
Slow or poor wound healing
Numbness at the surgery site
The wound splitting open where the incision (surgical cut) was made. This is only a risk if your wound is closed with sutures (stitches).
What to Expect When Having Mohs Surgery
You will receive important information about how to prepare for your surgery and have time to review it and ask questions. If you are having a plastic surgeon close your wound, you will get more information.
Your health care provider will review your medications and health history.
If you develop any illness (fever, cold, sore throat or flu) or are hospitalized before your surgery, call your health care provider’s office.
Depending on how many layers of tissue need to be removed, you may be at Hoag for several hours. We recommend that you eat breakfast and bring lunch or snacks with you. We can store your food, if needed.
If you have any questions, call your health care provider’s office.
How Long Does Mohs Surgery Take?
The length of your surgery depends on how many layers of tissue are removed. Be prepared to spend 2-3 hours at Hoag. Again, we recommend that you eat breakfast and bring lunch or snacks with you. We can store your food, if needed.
During Mohs Surgery
First, you will get an injection (shot) of local anesthesia to numb the surgery site. Once the area is numb, the cancerous tissue and a thin layer of surrounding tissue will be removed. A bandage will be placed on your wound.
After your wound is bandaged, you will stay in the procedure room. You can relax and eat light snacks or your lunch while you wait.
A lab will process and examine the removed tissue. If there are cancer cells at the border (edge) of the tissue, they will need to remove another layer of tissue.
These steps will be repeated until they find no more cancer cells at the borders of the tissue.
Closing Your Wound
After all the cancer is removed, you and your doctor will discuss the best way for your wound to close and heal. Examples include:
Allowing the wound to heal by itself.
Suturing the wound.
Creating a skin graft or flap to close the wound. A skin graft or flap is tissue that’s taken from one part of your body and moved to the area that must be covered.
Having a plastic surgeon close the wound. If you need to have a plastic surgeon close your wound, this must be planned ahead of time.
Before you leave Hoag, you will get instructions about how to care for your wound at home. You will also be told when you need to come back for your follow up appointment.
You will be able to go home right after your procedure.
You may have pain after your surgery. If you have pain, try taking extra strength acetaminophen (such as Tylenol Extra Strength).
If you are allergic to acetaminophen or cannot take it due to a medical condition, ask your health care provider what you can take instead.
Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil) or naproxen (Aleve) unless your health care provider says it is OK. These medications can cause bleeding.
You can also hold an ice pack over your wound to reduce pain and swelling. Hold the ice pack for 15 to 20 minutes every hour or follow the instructions your health care provider gives you.
If you have sutures, do not lift anything heavier than 15 pounds. The sutures will be removed during a follow-up appointment.
Do not exercise or travel on a plane for two weeks after your surgery.
Vectra WB360 3D Total Body Photographic Imaging
Hoag is the first hospital on the West Coast to offer high-risk skin cancer patients access to the Vectra WB360 as part of its comprehensive Melanoma & Skin Cancer Program.
Map, Monitor & Track Skin Lesions
The Vectra WB360 is a walk-through machine that has 92 cameras that flash simultaneously to capture a patient’s entire skin surface in less than one second. Powered by an advanced photographic software that uses artificial intelligence, the system generates a 3D avatar of a patient’s entire body and maps out all moles and lesions with high-resolution fidelity.
The system allows dermatologists at the Hoag Dermatologic Oncology program to monitor suspicious lesions and track changes over time, helping dermatologists detect skin cancer at the earliest stage, while avoiding unnecessary skin biopsies.
Hoag patients are now among the first in the nation to have access to the VECTRA WB360’s advanced technology.
"This highly innovative total body photographic imaging system will allow our dermatologists to monitor suspicious lesions and track changes over time." - Steven Q. Wang, M.D., Director Dermatologic Oncology & Chief of Dermatology
Watch our video to learn more about this groundbreaking technology.
Vectra WB360
Vectra WB360 - Media Coverage
Common Questions
You must first book a consult exam with our oncologic dermatologist, who will determine if you are eligible during the appointment. Depending on your insurance, this consult may be covered by insurance.
The cost of the Vectra total body photographic imaging is $595. Please note that physician fees are billed separately from the Vectra fee.
Currently, most insurance providers in California do not cover this total body photographic imaging or the physician fees associated with the session.
To schedule an appointment, call (949) 557-0275.
Be prepared to spend 20 to 30 minutes at your appointment.
Usually less than 5 seconds.
No, these are photos taken with special digital cameras. There is no radiation.
Yes, you may view the photos at the next appointment, either with our oncologic dermatologist.
Most patients will only need to have photos taken by the Vectra WB360 once every 5 to 7 years.
Meet the Melanoma & Skin Cancer Team
Melanoma & Skin Cancer Specialists and Surgeons

Steven Q. Wang, MD
Medical Director, Dermatologic Oncology

Thomas N. Wang, MD
Medical Director, Melanoma & Complex Skin Cancer Program
Melanoma & Skin Cancer Medical Oncologists

Simon Khagi, MD
Medical Director, Neuro-Oncology

Chaitali S. Nangia, MD
Co-Director, Breast Medical Oncology
Radiation Oncologists

Craig A. Cox, MD
Medical Director, Radiation Oncology Program

Peter V. Chen, MD
Radiation Oncology

Brian S. Kim, MD
Radiation Oncology

Kevin Lin, MD
Radiation Oncology

Shane A. Lloyd, MD
Radiation Oncology
Melanoma & Skin Cancer Nurse Navigator

Traci Swenson, BSN, RN, OCN
Oncology Nurse Navigator
Hoag's Precision Medicine Program
Hoag’s Precision Medicine Program combines genomics and genetics to diagnose, treat, and prevent diseases. Using the latest advances in genomic technologies, targeted therapies and research, our precision medicine program brings together a multidisciplinary team, including a robust genetic counseling group of experts, to provide patients with the latest in innovation and technology.
Hoag Family Cancer Institute Genetic Counselors
Hoag Family Cancer Institute provides a dedicated team of genetic counselors that offer hereditary cancer assessment, offering risk assessment and genetic cancer testing to those with a personal or family history of cancer.
Hoag Family Cancer Institute Social Workers
Being diagnosed with cancer can feel overwhelming at times. Many patients and their families need help with coping and can benefit from supportive counseling. Oncology Clinical Social Workers are available to provide emotional and practical support during all stages of cancer including diagnosis, treatment and post-treatment survivorship.
Hoag Family Cancer Institute Dietitians
Hoag Family Cancer Institute dietitians work closely with patients’ physicians, nurses, therapists, and social workers to ensure complete care.
Do I have Melanoma?
Melanoma is a type of skin cancer that originates in the melanocytes, the cells that produce pigment in the skin. Melanomas can develop anywhere there is pigmented skin, even on internal organs or the eyes, but most often occur on parts of the body exposed to the sun, including the face, arms, back and legs.Though melanoma is very treatable if diagnosed early, it is considered the most dangerous type of skin cancer due to its quick growth and ability to spread to any organ inside the body. Though only about 1 percent of all diagnosed skin cancers in the U.S. are melanoma, the disease causes the majority of skin-cancer-related deaths.
At Hoag, Our Whole-Body, Patient-First Philosophy Is All About You
Helping to limit anxiety and calm fears, when patients come to us with a potentially worrisome blemish, spot or mole, our skin exams are detailed and thorough, helping patients feel confident and comfortable. Our team sees every exam as an opportunity to educate and our world-class team of specialists take the time to explain as we examine, helping patients not only understand why one mole is safe while another is potentially malignant, but also which specific factors lead to that determination.
At Hoag, we understand the power of seeing every patient as a whole person, not just a name on a chart. And it’s another great reason to trust Hoag for your dermatologic care.
The most frequent early symptom of melanoma is finding a previously-unnoticed spot on the skin, or changes to the size, shape or color of an existing mole or blemish.
In evaluating suspect spots, moles or blemishes, the CDC suggests that those deciding whether to consult their doctor should remember “A-B-C-D-E.” It stands for:
Asymmetry: If you divide the spot in two, does it have an irregular shape that makes the two halves look different?
Border: Is the border of the spot uneven, irregular or jagged?
Color: Is color in the spot unevenly distributed across its surface?
Diameter: Is the spot larger than the diameter of a standard pencil eraser?
Evolving: Has the spot noticeably changed in color, size, shape or other characteristics over a period of weeks or months?
If the answer to one or more of these questions is yes, be safe and see your doctor.
There are a number of factors that are believed to increase your risk of developing melanoma.
Certain individuals are at higher risk for melanoma. These may include:
Fitzpatrick skin types I, II
Type I – described as skin that always burns, never tans and is sensitive to UV exposure
Type II – described as skin that burns easily, tans minimally
Excessive UV light exposure: excessive exposure to the sun or using indoor tanning beds
A history of severe, blistering sunburns
Family history of melanoma
Personal history of non-melanotic skin cancers
However, not all melanomas are at high risk. Here are some additional, more specific, risk factors for melanoma:
Having fair skin
A previous diagnosis of melanoma
Having more than 50 moles on your skin
Diagnosis with dysplastic nevi, which are a variety of moles which tend to be larger, and of an irregular color and shape
A weakened immune system (immunosuppression)
Familial melanoma
CDKN2A or CDK4 mutations
Melanocortin 1 Receptor Genotype
Childhood cancer survivors (previous treatment with XRT)
Parkinson’s Disease
Ways to reduce your risk of developing melanoma may include:
Check your skin regularly
Avoid purposeful tanning, whether in the sun or in a tanning bed
Avoid the sun during the middle of the day
Wear sunscreen when outdoors, year round, as the Skin Cancer Foundation says that daily use of sunscreen of at least 15 SPF can lower your risk of developing melanoma by at least 50 percent.
Limit your exposure to the sun while working outdoors through seeking shade, wearing clothing that covers more of your skin, applying a high-SPF sunscreen or working in the morning or late afternoon
The simplest step is to visit your dermatologist for a skin check-up once a year, or every six months if you have a family history.
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