Welcome to Pickup Family Neurosciences Institute
Your brain is who you are. Where you live. How you experience the world around you. As the most comprehensive neurologic care program in Orange County, our goal is to enhance your brain, repair damage, restore and improve your ability to be YOU.
You plan for everything.
We're here for the things you can't plan for. Our integrated, multidisciplinary neurosciences programs are evidence-based, use state-of-the-art technology and advanced clinical research, all focused on you.
Welcome to Pickup Family Neurosciences Institute
Pickup Family Neurosciences Institute offers world-class expertise in most conditions of the brain, spine, and peripheral nerves leveraging our multidisciplinary program approach, each focusing on a specific patient issue.

Hoag's relentless pursuit of excellence, its pride, is exemplified by PFNI. We are proud of the people, enabled by the facilities, and armed by the latest advanced technology that we - and our amazingly generous supporters - share with our entire community.
Ron & Sandi Simon Executive Medical Director Endowed Chair,
Pickup Family Neurosciences Institute
Neurological Specialties
- Acute Rehabilitation
- Get Started
- Addiction Medicine
- ASPIRE
- Concussion/Mild TBI
- Brain & Spine Cancer
- Epilepsy
- Headache
- Memory & Cognitive Disorders Program
- Mental Health Services
- Movement Disorders & Parkinson’s
- Multiple Sclerosis & Neuroimmunology Program
- Pain and Neuropathy
- Neurobehavioral Health
- Skull Base & Pituitary Tumors
- Stroke Program
- Sleep Health
- Young Adults Mental Health Program
Annual Report
How the Pickup Family Neuroscience Institute is making a difference in the field
Our expert specialized clinicians and supporting dedicated staff continue to commit themselves every day to provide outstanding results.
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Read MoreInstitute Awards
Access World-Class Neurosciences Care
The 2023-2024 U.S. News and World Report ranked Hoag high performing in Stroke and one of the best hospitals in Neurology and Neurosurgery.
Hoag leads the way
We are listed in the top 100 of approximately 4,500 hospitals in the nation for neurology and neurosurgery by U.S. News & World Report.
Our Locations
3900 West Coast Hwy.
Newport Beach, CA 92663
1 Hoag Drive
3rd Floor West Tower
Newport Beach, CA 92663
After School Program: Intervention and Resiliency Education (ASPIRE)
ASPIRE at Hoag Irvine
Contact: 949-557-0670
16100 Sand Canyon Ave., Suite 150
Irvine, CA 92618
After School Program: Intervention and Resiliency Education (ASPIRE)
ASPIRE at Hoag Newport Beach
Contact: 949-764-6360
307 Placentia Ave., Suite 109B
Newport Beach, CA 92663
3900 West Coast Hwy.
Newport Beach, CA 92663
1 Hoag Drive
Newport Beach, CA 92663
Brain Tumor
Marilyn Herbert Hausman Advanced Technology Pavilion (ATP)
Contact: 949-764-5938, Opt. 4
1 Hoag Drive
Newport Beach, CA 92663
3900 West Coast Hwy.
Newport Beach, CA 92663
Memory & Cognitive Disorders – Orange County Vital Brain Aging Program (OCVBAP)
Melinda Hoag Smith Center for Healthy Living
Contact: 949-764-6066
307 Placentia Ave.
Newport Beach, CA 92663
Memory & Cognitive Disorders – Orange County Vital Brain Aging Program (OCVBAP)
Pickup Family Neurosciences Institute
Contact: 949-764-6066
3900 West Coast Hwy.
Newport Beach, CA 92663
Memory & Cognitive Disorders – Orange County Vital Brain Aging Program (OCVBAP)
Hoag Health Center Irvine
Contact: 949-764-6066
16405 Sand Canyon Ave., Suite 260
Irvine, CA 92618
520 Superior Ave, Suite 205
Newport Beach, CA 92663
3900 West Coast Hwy., Ste. 300
Newport Beach, CA 92663
16405 Sand Canyon Ave.
Irvine, CA 92618
3900 West Coast Hwy., Suite 300
Newport Beach, CA 92663
510 Superior Ave., Suite 200A
Newport Beach, CA 92663
16305 Sand Canyon Avenue, Suite 230
Irvine, CA 92618
520 Superior Ave.
Newport Beach, CA 92663
16305 Sand Canyon Ave.
Irvine, CA 92618