Diagnosis & Treatment

Marfan syndrome and related connective tissue conditions are diagnosed in a number of ways. At Hoag, we offer a dedicated clinic to expertly diagnose these conditions, utilizing:

• Physical exam
• Echocardiogram
• Genetic testing & family history review
• Advanced imaging including 3D CT and MRI

Although, there is no curative treatment for Marfan syndrome and related conditions yet, with proper medical management and surveillance we can greatly improve quality of life and restore longevity to near normal. Our goal at Hoag is to have each of our patients live the longest and fullest life possible.

Toward that goal, Hoag Marfan Syndrome and Related Conditions Program in the Elaine & Robert Matranga Aortic Center offers:

• Ongoing medical guidance and management
• Blood pressure management
• In clinic echocardiogram
• On site 3D Imaging Lab evaluation
• State-of-the-art surveillance
• Surgical consultation

The program is led by Cardiovascular Specialist David Liang, M.D., Ph.D. who is internationally recognized for his care of patients with Marfan syndrome and related connective tissue conditions. Dr. Liang brings 25 years of experience with Marfan syndrome and related conditions.

Marfan syndrome patients are at an increased risk for aortic disease - when the aorta enlarges and the walls of the aorta are thinned. This can lead to aortic dissection (a tear) or rupture, which requires expert surgical care. Hoag’s Elaine & Robert Matranga Aortic Center is one of few centers in Southern California to provide a comprehensive approach to aortic disease. Hoag has two cardiothoracic surgeons dedicated to aortic surgery on staff for both elective and emergency surgery, Asad Shah, M.D., and director of Hoag Cardiovascular Surgery, Hoag’s Elaine & Robert Matranga Aortic Center and the Newkirk Family Endowed Chair in Aortic Care, Anthony Caffarelli, M.D. They bring the full spectrum of aortic surgery expertise, including valve-sparing aortic root replacement surgery which restores patients with aortic root aneurysms near normal life avoiding the use of blood thinners.

Marfan syndrome and related conditions impact the entire body, so the program incorporates ophthalmologists, orthopedists, maternal fetal medicine specialists, genetic counselors, podiatrists and physical therapist to provide coordinated and specialized care.