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Clinical Trials Advance Cancer Treatments Here at Home

Nearly every breakthrough in cancer treatment started out as a clinical trial. Now, Hoag offers access to cancer drugs that are often not available outside specialized cancer centers.

Through an alliance with USC Norris Comprehensive Cancer Center and with generous philanthropic support, Hoag will be ushering in a new era of research that will allow the team to offer the full spectrum of cancer care.

“Millions of lives have been saved by the scientific progress that clinical trials afford,” said Burton Eisenberg, M.D., Grace E Hoag Executive Medical Director Endowed Chair of Hoag Family Cancer Institute, and Professor of Clinical Surgery for Keck School of Medicine of USC. “Through our collaborative alliance with USC Norris Comprehensive Cancer Center, Hoag is able to fulfill its quest to advance medicine and improve our patient’s lives for generations to come.”

Hoag has initiated its participation with a phase I clinical trial testing a new drug for patients with advanced solid tumors. While it is rare for a community hospital to participate in early stage clinical trials, Hoag has long strived to offer the community the very latest in cancer therapies, allowing them to stay close to home for their care.

Phase I trials are particularly challenging as they typically involve testing the safety of a new drug or treatment in people for whom standard therapies have failed.

As challenging as such trials are, they’re a good fit for Hoag, which has always combined the ambition and pioneering spirit of a cutting edge hospital with the heart of a community hospital.

“Usually, these are the patients who have had to travel out of the county – or even out of the state – to receive care,” Dr. Eisenberg said. “By bringing phase I trials to Hoag, we are redoubling our commitment to providing the most innovative health care to our community.”

This initial trial will study the side effects and best dose of EphB4-HSA, a drug researchers hope will prevent the growth of tumor cells when given in combination with standard chemotherapy drugs for patients with advanced pancreatic, biliary, head and neck, and non-small cell lung cancer.

The trial will only be available at Hoag and USC Norris.

“This is a unique opportunity for our entire community,” said Dr. Eisenberg. “We are extremely excited to be able to expand what we can offer patients in Orange County, working closely with our alliance partners at USC Norris Comprehensive Cancer Center, and to take our place on the frontlines in the advancement of cancer medicine.”

For more information, call 888-648-2608.