Innovative Treatment Options Tailored to the Patient

The Hoag-USC Surgical Center for Digestive Disorders is a high-volume referral center for complex gastrointestinal disorders. Hoag’s multidisciplinary team of gastroenterology experts works together to thoroughly review and determine the best treatment option suited to each individual patient. The team then carefully tailors a personalized treatment plan to effectively achieve the best possible outcome for the patient. This emphasis on a collaborative, comprehensive approach to patient-centered care is why Hoag patient outcomes rank are among the nation’s best.

There is no cure for gastroparesis but several treatments are available that improve symptoms and offer a more comfortable lifestyle. Often, a multi-therapy approach is necessary to control symptoms of gastroparesis. That’s why it’s important to seek care at a center experienced in the diagnosis and treatment of gastroparesis and other chronic gastrointestinal disorders.

Nutrition/Diet Modification

First line treatment generally focuses on nutrition education and diet modification. The purpose of diet modification is to reduce symptoms and maintain adequate fluids and nutrition. A modified diet typically consists of liquids, restricted fats and plant fiber, and frequent small meals.

Medication Therapy

The most common medications used to treat gastroparesis symptoms include:
Prokinetic drugs, which are used to improve the rate of stomach emptying and thereby reduce nausea and vomiting. Examples include erythromycin (an antibiotic) and Reglan® (metoclopramide).
Antiemetic drugs, which are used to control nausea and vomiting but have no effect on stomach emptying. Examples include Compazine® (prochlorperazine) and Phenergan® (promethazine).

Enteral Nutrition Therapy

This therapy involves the delivery of liquid nutrients via a tube placed directly into the stomach or small intestine. Feeding tubes are usually temporary and used only when gastroparesis is severe.

Total Parenteral Nutrition (TPN)

TPN supplies nutrients to a person’s bloodstream through an intravenous (IV) infusion. TPN is used only if enteral feeding is not tolerated or is insufficient to meet caloric needs.


Surgery for gastroparesis is considered a treatment of last resort. Enterra Therapy is the latest advance (discussed below). Other surgical procedures include:
Pyloroplasty is performed to widen the pyloric valve (the muscle that separates the stomach from the upper region of the small intestine or duodenum).

Laparoscopic Subtotal Gastrectomy is a minimal invasive surgical approach that removes large parts of the diseased stomach, including the antrum of the stomach, but leaves behind a large enough portion of stomach to have an excellent quality of life. The removal of the diseased stomach helps the improvement of decreased nausea and vomiting after surgery.

Enterra® Therapy

This innovative surgical option is indicated for patients who are unresponsive to medication therapy and have chronic symptoms of nausea and vomiting due to gastroparesis of diabetic or idiopathic origin. Enterra Therapy uses a neurostimulator that is implanted beneath the skin and connected to two leads implanted in stomach muscle.

The Most Advanced Treatment Options Are Now Available in Orange County!

When it comes to seeking out the most advanced academic-level gastrointestinal care, there is no longer any need to travel long distances. The Hoag Digestive Disease Center, in alliance with USC Norris Comprehensive Cancer Center, offers the latest in state-of-the-art diagnosis and leading-edge treatment options that may not be readily available at other centers, including participation in clinical trials that helps to bring advanced gastrointestinal care to even more patients.

Perhaps the most distinguishing aspect of Hoag’s advanced treatment of gastrointestinal conditions is that in each and every case, treatment is always specifically tailored to the meet the unique needs of the individual patient.

Expert Care You Can Trust!

The Hoag Digestive Disease Center, in alliance with USC Norris Comprehensive Cancer Center, continues to lead the way in complex gastrointestinal care, providing access to a highly specialized surgical team that works collaboratively with Hoag-affiliated gastrointestinal surgeons, gastroenterologists and other medical specialists to provide academic-level care. Hoag’s committed to accurate diagnosis, combined with progressive therapeutic options enables Hoag patients to achieve some of the highest clinical outcomes in the nation.

To schedule a comprehensive diagnostic evaluation, or a second-opinion consultation with a Hoag gastroenterology expert, visit Meet the Team, or call us at: 888-566-9712.