Multiple Sclerosis & Neuroimmunology Program
520 Superior, Suite 350, Newport Beach, CA 92663
(949) 764-1850
- About
- Diagnosis
- Treatments
- Advances in MS Care
- Multiple Sclerosis Hope Center
- Meet the Team
- FAQs
Diagnosis of Multiple Sclerosis
Getting an accurate diagnosis of multiple sclerosis (MS) is one of the most important steps in your care journey. Because MS can mimic other neurological conditions, it requires specialized testing, advanced imaging, and expert evaluation by a neurologist who understands the complexities of this disease. At Hoag, our MS & Neuroimmunology Program is dedicated to providing clarity and confidence for patients seeking answers.
Why Accurate Diagnosis Matters
A misdiagnosis can delay the right treatment, cause unnecessary exposure to medications, and allow MS to progress unchecked. Early, precise diagnosis ensures that treatment can begin sooner, helping to preserve brain and spinal cord function and prevent long-term disability.
Advanced Imaging with Icometrix
Hoag is one of the few centers to integrate Icometrix, an advanced artificial intelligence tool that enhances MRI imaging. This technology provides detailed measurements of brain volume, lesion load, and subtle changes that may not be visible on standard scans. By using Icometrix, our specialists gain a clearer picture of disease activity, making it possible to diagnose MS earlier and track its progression with greater accuracy. While this technology enhances the imaging of the brain, it's the specialist who makes the diagnosis based on years of training and understanding of multiple sclerosis and how the lesions present on these images.
The Role of a Specialist Neurologist
MS is a complex disease that requires the expertise of a neurologist trained in MS and neuroimmunology. General neurology care may miss subtle signs or lead to delays in diagnosis. At Hoag, our patients benefit from comprehensive evaluations that consider medical history, neurological exam, bloodwork, spinal fluid analysis, and advanced imaging. This thorough process reduces the risk of misdiagnosis and ensures the most effective treatment plan.
Process
What to Expect in the Diagnostic Process
At Hoag, your evaluation may include:
Detailed neurological exam – assessing strength, coordination, reflexes, vision, and sensation.
Advanced MRI scans with Icometrix – providing objective measurements of brain and spinal cord changes.
Lumbar puncture (spinal fluid test) – detecting inflammatory markers that support MS diagnosis.
Blood tests – ruling out other autoimmune or infectious conditions that can mimic MS.
This comprehensive approach allows us to move beyond uncertainty and provide a clear diagnosis, so you and your care team can begin building a personalized treatment plan.
Why Choose Hoag
With advanced imaging, world-class expertise, and a patient-first philosophy, Hoag offers one of the most trusted MS diagnostic programs in the region. Our goal is not only to identify the disease accurately but also to guide patients with compassion and clarity from the very first appointment.
Your MS and Neuroimmunology Specialist

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