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Gastric Cancer
Hoag Family Cancer Institute
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Meet Hoag's Gastric (Stomach) Cancer Team
Gastric Cancer Surgeons

Katherine S. Blevins, MD
Foregut Surgery, Bariatric and General Surgery
Melissa L. DeSouza, MD
Foregut Surgery, Bariatric and General Surgery

Ronald F. Wolf, MD
Medical Director, Hepatobiliary and Pancreas Surgery
Gastric Cancer Medical Oncologists

Carlos R. Becerra, MD
Margaret Givan Larkin Endowed Chair in Developmental Cancer Therapeutics

Tara E. Seery, MD
Medical Director, Hepatobiliary Cancer
Radiation Oncologists

Craig A. Cox, MD
Medical Director, Radiation Oncology Program

Peter V. Chen, MD
Radiation Oncology

Brian S. Kim, MD
Radiation Oncology

Kevin Lin, MD
Radiation Oncology

Shane A. Lloyd, MD
Radiation Oncology
Advanced Endoscopists

Kenneth J. Chang, MD
James & Pamela Muzzy Executive Medical Director Endowed Chair in GI Cancer, Digestive Health Institute, Gastroenterology

Phuong T. Nguyen, MD
Medical Director of Hoag Advanced Endoscopy Center, Gastroenterology

Ravi J. Kankotia, MD
Gastroenterology

Paul J. Korc, MD
Medical Director Hoag GI Lab, Gastroenterology
Pathology

David R. Braxton, MD
Medical Director, Hoag Molecular Pathology
Gastric Cancer Nurse Navigator

Diane Eadie, RN, BSN
Clinical Nurse Navigator
Hoag's Precision Medicine Program
Hoag’s Precision Medicine Program combines genomics and genetics to diagnose, treat, and prevent diseases. Using the latest advances in genomic technologies, targeted therapies and research, our precision medicine program brings together a multidisciplinary team, including a robust genetic counseling group of experts, to provide patients with the latest in innovation and technology.
Hoag Family Cancer Institute Social Workers
Being diagnosed with cancer can feel overwhelming at times. Many patients and their families need help with coping and can benefit from supportive counseling. Oncology Clinical Social Workers are available to provide emotional and practical support during all stages of cancer including diagnosis, treatment and post-treatment survivorship.
Hoag Family Cancer Institute Dietitians
Hoag Family Cancer Institute dietitians work closely with patients’ physicians, nurses, therapists, and social workers to ensure complete care.
Hoag is dedicated to providing advanced gastroesophageal care, offering access to highly specialized diagnostic and treatment therapies led by an integrated team committed to delivering superior outcomes in gastric cancer care.
Are you concerned about your risk for cancer?
Explore our Cancer Prevention, High Risk & Early Detection Network for information regarding prevention, surveillance, screenings, assessments and more.
Groundbreaking Clinical Trials & Research
Hoag leads innovative clinical trials, including immunotherapy agents, all pushing for more advanced, effective care for gastric cancer patients.
Supportive Resources
Hoag is the top choice for cancer care in Orange County, with cancer survival rates that continually exceed national averages. Our dedicated, world-class teams are wholly focused on helping you survive cancer, heal and move forward with your life.

Gastric Cancer Overview
Gastric cancer is term used to describe cancer that occurs in the stomach. The most common type of stomach cancer occurs within the mucus-producing cells on the inside lining of the stomach (adenocarcinoma). Over time, the cancer may invade more deeply into the stomach wall and may grow through the stomach’s outer layer into nearby organs, such as the liver, pancreas, esophagus, or intestine.
It’s important to note that over the decades true gastric cancer has continued to decline. However, cancers of the junction between the esophagus and stomach are increasing. These latter tumors appear to be more similar to esophageal cancers rather than true gastric cancer.
Signs and symptoms of gastric cancer may include:
Anemia
Fatigue
Feeling full and/or bloated after eating small amounts of food
Heartburn and/or indigestion
Stomach pain
Persistent nausea and/or vomiting
Unexplained weight loss
Because gastric cancer symptoms are similar to many other gastrointestinal conditions, accurate evaluation is critical to ensure proper treatment. That’s why it’s important to seek care from a health care expert experienced in the complex diagnosis and treatment of gastric cancer and other gastrointestinal conditions.
The exact cause of gastric cancer is unknown. However, factors that may increase an individual’s risk of stomach cancer include:
A diet high in smoked, salted and pickled foods
A diet low in fruits and vegetables
Eating foods contaminated with aflatoxin fungus
Family history of stomach cancer
Infection with Helicobacter pylori
Long-term stomach inflammation
Pernicious anemia
Smoking
Stomach polyps
Expert Care You Can Trust

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Contact usExpert Diagnosis is Key
Comprehensive evaluation with accurate diagnosis is the foundation for achieving highly successful outcomes. That’s why it’s important to seek care from a center that provides academic level care from a multidisciplinary, specialized team of gastrointestinal experts experienced in the accurate diagnosis of gastric cancer, as well as other complex gastrointestinal disorders.
Beginning with a thorough evaluation that includes a comprehensive physical exam, personal medical history review and state-of-the-art diagnostic workup, Hoag’s multidisciplinary team of board-certified, fellowship trained gastrointestinal experts carefully evaluate and pinpoint the nature of the issue, so the most appropriate personalized treatment options can be employed.
Hoag’s state-of-the-art diagnostic technologies provide our team with the latest modalities in the accurate diagnosis of gastric cancer and other disorders. Some of the progressive imaging studies that may be utilized include:
Upper Gastrointestinal Endoscopy is a minimally invasive procedure that allows a physician to look inside the esophagus, stomach, and duodenum (part of the small intestine). During an upper endoscopy, a thin, lighted tube called an endoscope is carefully guided down the esophagus. The endoscope transmits a high definition image to a monitor, so the physician can view the lining of these organs. Endoscopy allows physicians to visualize evidence of gastrointestinal disorders, as well as remove tissue samples for biopsy. Hoag surgeons typically perform the endoscopy themselves in order to assess how much of the stomach is involved for surgical planning.
Biopsy is the removal of a sample of tissue for testing. This procedure is performed to definitively diagnose gastric cancer, and usually takes place via endoscopy.
Computed Tomography (CT) utilizes state-of-the-art x-rays to help determine the extent of the cancer and whether it encompasses the surrounding organs.
Positron Emission Tomography (PET) is a nuclear medicine imaging technique which produces a three-dimensional image that helps determine the extent of the cancer and whether it has spread to the lymph nodes.
Endoscopic Ultrasound (EUS) is a specialized endoscope that also has ultrasound capabilities. EUS can evaluate and assess the size of the tumor, lymph node status and Stage of the tumor.
It’s important to note that proper diagnosis of gastric cancer is critical to developing a successful treatment plan. That’s why it’s so important to seek proper evaluation and treatment from a healthcare expert experienced in the most advanced gastrointestinal care.
Innovative Treatment for Gastric Cancer
When it comes to gastric cancer and other gastrointestinal conditions, Hoag provides a full array of progressive treatment options. As a recognized leader and high-volume provider of innovative gastrointestinal care, Hoag’s multidisciplinary team of digestive disease experts performs some of the most advanced gastroenterology procedures available in the nation with clinical outcomes that rival national figures.
Expert Care You Can Trust
Hoag continues to lead the way in complex GI care, providing access to a highly specialized surgical team that works collaboratively with Hoag thoracic surgeons, gastroenterologists and medical oncology specialists to provide expert care. Hoag’s committed to accurate diagnosis, combined with progressive therapeutic options enables Hoag patients to achieve some of the highest clinical outcomes in the nation.To schedule a comprehensive diagnostic evaluation, or a second-opinion consultation with a Hoag gastroesophageal expert, call us at: (888) 566-9712.
Innovative Treatment Options Tailored to the Patient
Hoag is a high-volume referral center for complex gastrointestinal disorders.
Hoag’s multidisciplinary team of gastroenterology experts works together to thoroughly review and determine the best treatment option suited to each individual patient. The team then carefully tailors a personalized treatment plan to effectively achieve the best possible outcome for the patient. This emphasis on a collaborative, comprehensive approach to patient-centered care is why Hoag patient outcomes rank are among the nation’s best.
Once gastric cancer is diagnosed, important staging tests are performed to determine if the cancer has spread, and if so, to what extent. The type of treatment recommended depends upon the stage of the cancer and may include options such as:
Surgery
The standard of care for gastric cancer is surgical removal of the tumor with dissection of lymph node tissue around the surrounding structures. The amount of stomach removed depends on the size and location of the tumor. Surgery also removes as much of the lymph node tissue surrounding the stomach as possible to remove all potential regional sites of tumor spread and maximize the chance of cure.
When appropriate, minimally invasive techniques may be applied for the operation, such as state-of-the-art robotic and laparoscopic gastrectomy, which results in less scarring and discomfort, as well as a faster recovery time for the patient. The Hoag gastrointestinal surgical team has not only one of the highest volumes and expertise for innovative gastric cancer surgeries, but also the lowest morbidity and mortality rates.
Chemotherapy
Chemotherapy is the use of drugs to kill cancer cells. The drugs enter the bloodstream and travel through the body killing mostly cancer cells, but also some healthy cells. Chemotherapy is often combined with surgery in the treatment of gastric cancer. The utilization of chemotherapy is selective, and may be used before or after surgery.
Radiation Therapy
Radiation therapy uses radiation to kill cancer cells and shrink tumors. On occasion, radiation therapy may also be necessary in the treatment of gastric cancer based upon the type/stage of cancer. As a nationally recognized leader in state-of-the-art radiation therapies, Hoag’s Radiation Oncology Program is yet another example of the institute’s commitment to excellence in innovative cancer treatment.
Targeted Therapy
Targeted therapy uses drugs that attack specific abnormalities within cancer cells. The most common targeted therapies used to treat gastric cancer include:
Trastuzumab (Herceptin) for stomach cancer cells that produce too much HER2,
Imatinib (Gleevec) for a rare form of stomach cancer called gastrointestinal stromal tumor, and
Sunitinib (Sutent) for gastrointestinal stromal tumor.
Tests are performed on your cancer cells to help your physician to determine whether these targeted treatments are likely to work for you.
The Most Advanced Treatment Options Are Now Available in Orange County
When it comes to seeking out the most advanced academic-level gastrointestinal care, there is no longer any need to travel long distances. Hoag offers the latest in state-of-the-art diagnosis and leading-edge treatment options that may not be readily available at other centers, including participation in clinical trials that helps to bring advanced gastrointestinal care to even more patients.
Perhaps the most distinguishing aspect of Hoag’s advanced treatment of gastrointestinal conditions is that in each and every case, treatment is always specifically tailored to the meet the unique needs of the individual patient.
Expert Care You Can Trust
The Hoag Digestive Disease Center continues to lead the way in complex gastrointestinal care, providing access to a highly specialized surgical team that works collaboratively with Hoag-affiliated GI and medical oncology specialists. Hoag’s committed to accurate diagnosis, combined with progressive therapeutic options enables Hoag patients to achieve some of the highest clinical outcomes in the nation.
To schedule a comprehensive diagnostic evaluation, or a second-opinion consultation with a Hoag gastroenterology expert, call us at (949) 764-8379.
Gastric Cancer Treatments
Chemotherapy/Systemic Therapy
Chemotherapy uses powerful drugs or chemicals to directly attack cancerous cells. Systemic Therapy is a non-surgical treatment option for cancer patients. Systemic therapy is when drugs are administered into a patient’s blood stream to stop or slow the growth of cancerous cells. Biological therapy, also referred to as “Immunotherapy” utilizes the body immune system to fight cancer cells.
da Vinci® Robotic Surgery
The da Vinci® SP1 Surgical System is an innovative robotic platform that allows surgeons to perform complex surgeries through a single incision.
Precision Medicine Program
Hoag’s Precision Medicine Program combines genomics and genetics to diagnose, treat, and prevent diseases. Using the latest advances in genomic technologies, targeted therapies and research, our precision medicine program brings together a multidisciplinary team, including a robust genetic counseling group of experts, to provide patients with the latest in innovation and technology.
Radiation Oncology
Hoag’s Radiation Oncology Program offers the widest range of radiation therapy options available, ensuring every treatment plan is precisely tailored to each patient.
Tumor Boards
Tumor boards* are a meeting of Hoag’s top experts in their respective subspecialties to determine the best approach for a patient’s individual cancer case.
Palliative Care
Palliative care is a specialty that focuses on improving the quality of life of individuals facing serious illness through medical management and emotional support.
Cancer Clinical Trials
Early development clinical trials (phase I and II) are novel drug therapies that examine new treatments that provide options beyond standard of care. During these trials, researchers are carefully examining the best way to administer the treatment, determine how much can be safely given, identify important potential side effects, as well as assess cancer response.
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