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    Digestive Health Clinical Trials

    A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/​MASH

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    What is the purpose of this study?

    This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.

    Eligibility

    • Cohort 1: Biopsy proven compensated cirrhosis (fibrosis stage 4) due to NASH/MASH and NAS score of >=3 (at least 1 in each category) or evidence of steatosis and 2 current features of metabolic comorbidities
    • Cohort 2: Biopsy proven or non-invasively diagnosed compensated cirrhosis (fibrosis stage 4) due to NASH/MASH

    Where can I participate?

    Hoag Hospital Newport Beach
    1 Hoag
    Newport Beach, CA 92663


    Vianh Truong

    vianh.truong@hoag.org


    More about this Clinical Trial

    What is the full name of this Clinical Trial?

    A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

    • Disease Type/ConditionNASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis
    • Principal InvestigatorBrian T. Lee, MD
    • Co-InvestigatorsTse-Ling Fong, MD
    • Age GroupAdult, Older Adult
    • PhaseIII
    • ClinicalTrials.gov IDNCT06528314

    Hoag Digestive Health Institute

    Hoag Digestive Health Institute provides advanced, comprehensive care for the full spectrum of digestive conditions, with access to world-class specialists, diagnostics and imaging, advanced interventional therapeutics, and clinical trials. Patients benefit from a research-driven approach that connects leading-edge treatment options with personalized care across gastroenterology and GI surgery.

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