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    Esophageal Cancer

    (949) 722-6237

    Hoag is committed to complex gastroesophageal care, providing access to highly specialized diagnostic and treatment therapies, led by a team that works seamlessly together to provide excellent esophageal cancer care.

    Concerned about your risk for cancer?

    Explore our Cancer Prevention, High Risk & Early Detection Network for information regarding prevention, surveillance, screenings, assessments and more.

    Groundbreaking Clinical Trials & Research

    Hoag leads innovative clinical trials, including immunotherapy agents, all pushing for more advanced, effective care for esophageal cancer patients.

    Supportive Resources

    Hoag is the top choice for cancer care in Orange County, with cancer survival rates that continually exceed national averages. Our dedicated, world-class teams are wholly focused on helping you survive cancer, heal and move forward with your life.

    Doctor checking elderly man's lymph nodes

    What is Esophageal Cancer?

    Esophageal cancer occurs when cancer cells develop in the esophagus, a tube-like structure that runs from the throat down to the stomach. There are two main types of esophageal cancer – squamous cell carcinoma and adenocarcinoma.
    Esophageal female cancer patient

    Types of Esophageal Cancer

    Squamous Cell Carcinoma is a condition in which abnormal squamous cells (the cells that make up part of the mucous membrane that lines the esophagus) divide and spread uncontrollably. In the past, squamous cell carcinomas were responsible for nearly 90% of all esophageal cancers. However, they now make up less than 50% of esophageal cancers. Adenocarcinomas occur in glandular tissue and not in squamous tissue. Before an adenocarcinoma can develop, glandular cells must replace an area of squamous cells, as in the case of Barrett’s esophagus. This transformation is most common in the lower esophagus, which is the site of most adenocarcinomas.
    Doctor checking woman's nodes

    Risk Factors for Esophageal Cancer

    The following are the most common risk factors for esophageal cancer: smoking or other use of tobacco, heavy alcohol use, gastroesophageal reflux disease (GERD) and Barrett’s esophagus. In addition, men, the elderly, and African Americans are at greater risk for developing esophageal cancer.
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    Expert Care You Can Trust

    Hoag’s commitment to accurate diagnosis, combined with progressive therapeutic options enables Hoag patients to achieve some of the highest clinical outcomes in the nation.
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