I have high cholesterol—why does my doctor recommend a statin long term?

I have high cholesterol—why does my doctor recommend a statin long term?
One of the most common questions I hear is: “Why would I need to take a statin for the rest of my life?” It’s a reasonable question—and the answer is rooted in how cholesterol affects the body over time.
What statins do
Statins lower LDL cholesterol and reduce inflammation within blood vessels. More importantly, they have been shown to reduce the risk of heart attack and stroke in people at increased cardiovascular risk.
Why long-term treatment is often recommended
Cholesterol levels tend to rise again if treatment is stopped. That’s because:
Genetics play a significant role in cholesterol production
Age-related changes affect metabolism
Atherosclerosis develops over decades, not months
Statins are not just treating a lab value—they are reducing long-term cardiovascular risk.
Addressing common concerns
Many patients worry about side effects or dependency. In practice:
Most people tolerate statins well
Side effects are monitored and addressed promptly
Dosing and medication choice can be adjusted if needed
The goal is always the lowest effective dose to achieve risk reduction.
The bottom line
For patients at higher risk, statins are a preventive tool—not a punishment. When recommended, they are part of a broader strategy to protect heart health over the long term.
Learn more about Hoag’s newest primary care physicians and the Jeffrey M. Carlton Heart & Vascular Institute.

