Epilepsy Program

Overview

Hoag Epilepsy Program provides an individualized, comprehensive approach to the diagnosis, treatment, management, and research of epilepsy and seizure disorders. As an NAEC Level III Epilepsy Center, the multi-disciplinary team is dedicated to providing the safest, most effective and least invasive treatments to help patients achieve the highest functionality. The Hoag Epilepsy Program also includes an Epilepsy Monitoring Unit. Our three-bed unit offers a comfortable environment with state-of-the-art video monitoring. A control room is just steps away for quick access to patients, and is staffed 24 hours a day with EEG monitoring technicians

Team

The program is led by Dr. David Millett, a nationally recognized Epileptologist along with Drs. Jason Muir, M.D., and Andrew Ly, M.D. The nurse navigator for the Epilepsy Program is Sheena Dhiman, BSN, MBA. Her role is to work with the physicians, nurses, and EEG staff to help facilitate patient care, including appropriate referrals and resources, education of patients and staff, and coordinating programs to provide a large array of services to promote psychological and physiological wellness.

Patients in our Epilepsy Monitoring Unit are surveyed using the Quality of Life in Epilepsy (QOLIE -10P) assessment tool. The average patient in FY16 experienced a 153% improvement in quality of life. Patients with surgical resection for epilepsy have experienced 122 days of seizure freedom and our laser ablation patients have had 150 days of seizure freedom.

Support & Education

As part of a multi-disciplinary, collaborative approach to epilepsy, neurosurgeons, epileptologists, neuroradiologists, epilepsy care coordinators, EEG technologists and other health care professionals meet on a regular basis to review patient-specific cases being considered for surgical interventions. Patients benefit from this combined expertise and experience of the collective physicians and professionals.

The Epilepsy Center at Hoag offers an interactive support group for all adolescent and adult epilepsy patients. This support group functions under the direction of a licensed clinical social worker, and includes group and family discussions to help you better understand and cope with epilepsy. It meets on the first Wednesday of every month from 6:30 to 8 p.m. in the Hoag Neurosciences Institute, 3rd floor conference room.

The Hoag Epilepsy Program also offers patients and families an Epilepsy 101 class. This is a basic class about Epilepsy designed for the newly diagnosed, but is also a great class for family members and caregivers. It is a one-hour presentation where the basics of epilepsy are taught in an easy-to-understand format. This class is offered on an as-needed basis.

Clinical Research

UCB Pharma Protocol No1199: An open-label, multicenter, follow-up trial to evaluate the long-term safety and efficacy of Brivaracetam used as adjunctive treatment at a flexible dose up to 150 mg/day in subjects aged 16 years or older suffering from epilepsy. October 2013

Publications, Lectures, Book Chapters

BIBLIOGRAPHY (*indicates senior/corresponding author):

PEER REVIEWED

1. Millett D, Ashikian N, Lee R, Kim P. Neurocysticercosis in the U.S.: A single-center, single-year study of 451 patients in Los Angeles. Submitted


2. Hsiao MC, Yu PN, Song D, Liu CY, Heck CN, Millett D, Berger TW. Spatio-temporal inter-ictal activity recorded from human epileptic hippocampal slices. Conf Proc IEEE Eng Med Biol Soc. 2012 Aug;2012:5166-9.


3. Shaw S, Kim P, and Millett D. “Status Epilepticus Amauroticus Revisited: Ictal and Peri-ictal Homonymous Hemianopia,” Arch Neurol 69: 1504-1507, 2012

ABSTRACTS

1. Po T. Wang*, Christine E. King, Colin McCrimmon, Susan J. Shaw, David Millett, Charles Y. Liu, Luis A. Chui, Zoran Nenadic, An H. Do. “Electrocorticogram Encoding of Upper Extremity Movement Duration.” 36th Annual International IEEE EMBS Conference, Chicago, IL, August 26-30, 2014.


2. Pen-Ning Yu*, Min-Chi Hsiao, Dong Song, Charles Y. Liu, Christi N. Heck, David Millett, Theodore Berger. “Unstable Periodic Orbits in Human Epileptic Hippocampal Slices.” 36th Annual International IEEE EMBS Conference, Chicago, IL, August 26-30, 2014.


3. Min-Chi Hsiao, Pen-Ning Yu, Dong Song, Charles Y. Liu, Christi N. Heck, David Millett, Theodore Berger. “A Testbed to Explore the Optimal Electrical Stimulation Parameters for Suppressing Inter-Ictal Spikes in Human Hippocampal Slices.” 36th Annual International IEEE EMBS Conference, Chicago, IL, August 26-30, 2014.

CHAPTERS

1. Millett D, Coutin-Churchman P, Stern J. “Basic Principles of Electroencephalography.” In Toga A. Brain mapping: An Encyclopedic Reference. Elsevier Press, 2015: pp. 75-80.


2. Millett D and Stern J. “Fundamentals of EEG.” In Stern J and Sirven J (Eds), Atlas of Video-EEG Monitoring, McGraw-Hill, 2011.